Treatment of Gonorrhoea with Spiramycin

Treatment of gonorrhoea with spiramycin.

Spiramycin is a relatively new antibiotic prepared from Streptomyces ambofaciens which was first isolated from a soil sample by French workers. It was reported on by Pinnert-Sindico, Ninet, PreudHomme and Cosar at the Washington Symposium on Antibiotics in 1954. It is available as a sulphate in yellowish capsules each of 0-5 g. protected by a thin coat of varnish. So far there have been few rep...

Spiramycin in the Treatment of Acute Gonorrhoea.

Introduction The treatment of gonorrhoea in Denmark is as yet no serious therapeutic problem, as the majority of gonococcal infections can be cured by penicillin. Nevertheless, in an increasing number ofcases a higher dosage of penicillin is required than was the case just a few years ago. At the Dermato-venereological Department of the University Hospital, a single treatment dose of 300,000 un...

Treatment of non-gonococcal urethritis with spiramycin.

Treatment of gonorrhoea with amoxycillin.

The synthesis of the penicillin nucleus 6-aminopenicillanic acid was first achieved by Sheehan (1958), but it was not until the following year that a team of workers at the Beecham Research Laboratories discovered a method of producing the compound on a large scale, and thus made possible for the first time the synthesis of innumerable penicillin compounds. Until recently ampicillin, introduced...

Treatment of Gonorrhoea with Penbritin*

Although Sheehan (1958) had synthesized the penicillin nucleus 6-aminopenicillanic acid in 1958, it was not until 1959 that workers at the Beecham Research Laboratories (Batchelor, Chain, and Rolinson, 1961; Rolinson, Batchelor, Butterworth, Cameron-Wood, Cole, Eustace, Hart, Richards, and Chain, 1960) discovered a method of producing this compound on a large scale and made possible for the fir...